Medicinal plants used for the treatment and management of rheumatoid arthritis

Authors

  • Ameena Ahmed Faculty of Pharmaceutical Science, Assam downtown University, Guwahati, Assam 781026
  • Injamul Islam Faculty of Pharmaceutical Science, Assam downtown University, Guwahati, Assam 781026
  • Anubhab Borah Faculty of Pharmaceutical Science, Assam downtown University, Guwahati, Assam 781026
  • Ankita Sarkar Faculty of Pharmaceutical Science, Assam downtown University, Guwahati, Assam 781026
  • Shahil Arman Faculty of Pharmaceutical Science, Assam downtown University, Guwahati, Assam 781026

Keywords:

Rheumatoid arthritis, auto-immune disease, synovial inflammation, symptoms, diagnosis, medicinal plants

Abstract

Rheumatoid arthritis is an autoimmune disease. Patients suffering from rheumatoid arthritis experience severe pain in their joints. The joint pain is basically caused by systemic inflammation in joints and damaged cartilage and bones around the joint. The disease persists and develops in a patient resulting into disabilities. It affects the internal organs such as lung, heart and eyes. There is no known effective treatment that can cure rheumatoid arthritis. Modern medications are being used to treat only the symptoms associated with the disease albeit, modern medicines possess numerous disadvantages. Modern medicines can temporarily give relief the patient and the symptoms reappear upon discontinuation. The adverse effects of the modern medicines can hamper the therapeutic treatments also. The herbs and plants are proved to be a better alternative to treat pain and inflammation around the joints. In nature there is an abundance of medicinal plants that shows anti rheumatoid arthritis properties. So the plants and plant products with great advantages are utilized and used to treat rheumatoid arthritis. The aim of this review article is to update information on rheumatoid arthritis including causes, epidemiology, symptoms, diagnosis and classification of rheumatoid arthritis. The present review also highlights the medicinal plants having anti rheumatoid arthritis property

References

Firestein, G.S. Etiology and pathogenesis of rheumatoid arthritis. In: Ruddy S, Harris ED, Sledge CB, Kelley WN, eds. Kelley’s Textbook of Rheumatology. 7th ed. Philadelphia: W.B. Saunders, 996–1042 (2005).

Arya V, Gupta VK, Kaur R. A review on plants having anti-arthritic potential. Inter. J. Pharm. Sci. Rev. Res. 7(2), 024 (2011)

Soeken KL, Miller SA, Ernst E. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. Rheumatology 42, 652–659 (2003)

Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 423, 356-361 (2003)

Linos A, Worthington JW, O'Fallon WM, Kurland LT. The epidemiology of rheumatoid arthritis in Rochester, Minnesota: a study of incidence, prevalence, and mortality. Am. J. Epidemiology 111(1), 87-98 (1980)

Kobelt G. The social and economic impact of rheumatoid arthritis. In: Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatoid Arthritis. Philadelphia, Penn: Mosby Elsevier. 83-89 (2009).

Emery P, McInnes IB, van Vollenhoven R, Kraan MC. Clinical identification and treatment of a rapidly progressing disease state in patients with rheumatoid arthritis. Rheumatology (Oxford) 47(4), 392-8 (2008)

Rathore B, Mahdi AA, Paul BN, Saxena PN, Das SK. Indian herbal medicines; possible potent therapeutic agents for rheumatoid arthritis. J Clin. Biochem. Nutri. 41(1), 12-17 (2007)

Zakeri Z, Izadi S, Bari Z, Soltani F, Narouie B, Rad MG. Evaluating the effects of ginger extract on knee pain, stiffness and difficulty in patients with knee osteoarthritis. Journal of Medicinal Plants Research 5(15), 3375-9 (2011)

Bhalerao AR, Desai SK, Serathia BR, Vartak KM, Doshi GM. Anti-arthritic studies on Nyctanthes arbor tristis and Maharasnadi ghan. Der Pharmacia Lettre 3(4), 101-10 (2011)

Brindha P. Pharmacognostical and Phytochemical Studies on Hemidesmus Indicus Root. International Journal of Pharmacognosy and Phytochemical Research 3(3), 74-79 (2011)

Mehta A, Sethiya NK, Mehta C, Shah GB. Anti-arthritis activity of roots of Hemidesmus indicus R.Br. (Anantamul) in rats. Asian Pac J Trop Med 5(2), 130-5 (2012)

Sandoval M, Okuhama NN, Zhang XJ, Condezo LA, Lao J et al. Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content. Journal of Phytomedicine 9(4), 325-37 (2002)

Aguilar JL, Rojas P, Marcelo A, Plaza A, Bauer R, Reininger E, Klaas CA, Merfort I. Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae). J Ethnopharmacol 81, 271-6 (2002)

Soeken KL, Miller SA, Ernst E. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. Rheumatology (Oxford) 42, 652-9 (2003)

Boskabady MH, Aslani MR, Kiani S. Relaxant effect of Thymus vulgaris on guinea-pig tracheal chains and its possible mechanism(s). Phytother Res 20, 28-33 (2006)

Lee SJ, Umano K, Shibamoto T, Lee KG. Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties. Food Chem, 91, 131–7 (2005).

Pradeepkiran JA. Insights of rheumatoid arthritis risk factors and associations. J Transl Autoimmun 2, 100012 (2019)

Adhiparasakthi Engineering College. Department of Electronics and Communication Engineering, Institute of Electrical and Electronics Engineers. Madras Section, & Institute of Electrical and Electronics Engineers. (n.d.). ICCSP-2016?: 4th-6th April, 2016.

Downloads

Published

2024-01-26

How to Cite

Ahmed, A., Islam, I., Borah, A., Sarkar, A., & Arman, S. (2024). Medicinal plants used for the treatment and management of rheumatoid arthritis. Journal of Applied Pharmacognosy and Phytochemistry, 3(1), 01-06. Retrieved from https://www.joapponline.com/index.php/joapp/article/view/36

Issue

Vol. 3 No. 1 (2023)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

In submitting an article to Journal of Applied Pharmacognosy and Phytochemistry (JOAPP) I certify that:

  1. I am authorized by my co-authors to enter into these arrangements.
  2. I warrant, on behalf of myself and my co-authors, that:
    • the article is original, has not been formally published in any other peer-reviewed journal, is not under consideration by any other journal and does not infringe any existing copyright or any other third party rights;
    • I am/we are the sole author(s) of the article and have full authority to enter into this agreement and in granting rights to JOAPR are not in breach of any other obligation;
    • the article contains nothing that is unlawful, libellous, or which would, if published, constitute a breach of contract or of confidence or of commitment given to secrecy;
    • I/we have taken due care to ensure the integrity of the article. To my/our - and currently accepted scientific - knowledge all statements contained in it purporting to be facts are true and any formula or instruction contained in the article will not, if followed accurately, cause any injury, illness or damage to the user.
  3. I, and all co-authors, agree that the article, if editorially accepted for publication, shall be licensed under the  Creative Commons Attribution-NonCommercial 4.0 International License
  4. I, and all co-authors, agree that, if the article is editorially accepted for publication in Journal of Applied Pharmaceutical Research (JOAPR) data included in the article shall be made available under the Creative Commons 1.0 Public Domain Dedication waiver, unless otherwise stated. For the avoidance of doubt it is stated that sections 1, 2, and 3 of this license agreement shall apply and prevail.